Abstract
Basic Principles of Lyophilization, Part 2
Author(s): Akers Michael J
Issue: Jan/Feb 2016 - Volume 20, Number 1
Page(s): 20-27
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Abstract
The achievement of a high-quality lyophilized (freeze-dried) dosage form involves the combination of optimal formulation design and optimal freezedry cycle design. Part 1 of this 2-part article discussed the basic principles and procedures of lyophilization up to a discussion on the different stages of lyophilization. The stages of lyophilization are discussed within this article.
Related Keywords
- lyophilization
- freeze drying stages
- cooling-freezing
- primary drying
- secondary drying
- troubleshooting
- supercooling
- cooling rate
- protein stability
- parenteral process technology
- product formulation
- quality control
Related Categories
- PARENTERALS
- STABILITIES, COMPATIBILITIES
- TECHNOLOGY
- QUALITY CONTROL
- DOSAGE FORMS/DRUG CARRIERS
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