Abstract

Basic Principles of Lyophilization, Part 2

Author(s): Akers Michael J

Issue: Jan/Feb 2016 - Volume 20, Number 1

Page(s): 20-27

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  • Basic Principles of Lyophilization, Part 2 Page 8

Abstract

The achievement of a high-quality lyophilized (freeze-dried) dosage form involves the combination of optimal formulation design and optimal freezedry cycle design. Part 1 of this 2-part article discussed the basic principles and procedures of lyophilization up to a discussion on the different stages of lyophilization. The stages of lyophilization are discussed within this article.

Related Keywords

  • lyophilization
  • freeze drying stages
  • cooling-freezing
  • primary drying
  • secondary drying
  • troubleshooting
  • supercooling
  • cooling rate
  • protein stability
  • parenteral process technology
  • product formulation
  • quality control

Related Categories

  • PARENTERALS
  • STABILITIES, COMPATIBILITIES
  • TECHNOLOGY
  • QUALITY CONTROL
  • DOSAGE FORMS/DRUG CARRIERS

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