Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

Basic Principles of Lyophilization, Part 2

Author(s):  Akers Michael J

Issue:  Jan/Feb 2016 - Volume 20, Number 1
View All Articles in Issue

Abstract:  The achievement of a high-quality lyophilized (freeze-dried) dosage form involves the combination of optimal formulation design and optimal freezedry cycle design. Part 1 of this 2-part article discussed the basic principles and procedures of lyophilization up to a discussion on the different stages of lyophilization. The stages of lyophilization are discussed within this article.

Related Keywords: Michael J. Akers, PhD, lyophilization, freeze drying stages, cooling-freezing, primary drying, secondary drying, troubleshooting, supercooling, cooling rate, protein stability, parenteral process technology, product formulation, quality control

Related Categories: PARENTERALS, STABILITIES, COMPATIBILITIES, TECHNOLOGY, QUALITY CONTROL, DOSAGE FORMS/DRUG CARRIERS

Printer-Friendly Version




Download in electronic PDF format for $45

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Basic Principles of Lyophilization, Part 2 Akers Michael J Jan/Feb 2016 20-27 Buy
Basic Principles of Lyophilization, Part 1 Akers Michael J Nov/Dec 2015 471-476 Buy
Basics of Compounding for Dry-Skin Conditions Allen Loyd V Jr Nov/Dec 2003 460-463 View Sample
Basics of Sterile Compounding: Manipulating Peptides and Proteins Akers Michael J May/Jun 2017 223-228 Buy
Investigation of Filler Effects on the Compounding of Freeze-dried Orodispersible Tablets Containing Annona muricata Extract Azman Syahiera Ezzah Noor, Abd Razak Fashli Syafiq, Kamal Wan Hamirul Bahrin Wan, Zheng Gan Kok, Ming Long Chiau, Uddin ABM Helal, Sarker Zaidul Islam, Bin Liew Kai Nov/Dec 2020 509-514 Buy
Dry Heat Sterilization of Parenteral Oil Vehicles Kupiec Thomas C, Matthews Parrish, Ahmad Riaz May/Jun 2000 223-224 Buy
Operation of a Dry-Heat Sterilizing Oven and Validation of this Procedure Allen Loyd V Jr Nov/Dec 1999 488-489 Buy
Basics of Sterile Compounding: Excipients Used in Injections Akers Michael J Jul/Aug 2017 301-308 Buy
Formulation and Stability of Solutions Akers Michael J Mar/Apr 2016 137-141 Buy
Basics of Compounding for Sterile, Nonsterile, and Quality Control Compounding: Process Analytical Technology: Appropriate for Sterile and Nonsterile Compounding? Allen Loyd V Jr Mar/Apr 2019 123-130 Buy