Abstract

Basic Principles of Lyophilization, Part 1

Author(s): Akers Michael J

Issue: Nov/Dec 2015 - Volume 19, Number 6

Page(s): 471-476

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Abstract

The achievement of a high-quality lyophilized (freezedried) dosage form involves the combination of optimal formulation design and optimal freeze-dry cycle design. This 2-part article describes how this can be done. Part 1 discusses the basic principles and procedures of lyophilization up to a discussion on the different stages of lyophilization. The stages of lyophilization are discussed in part 2.

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