Abstract

Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care

Author(s): Guimarães Anna Luísa Aguiar, Cunha Elisa Alves, Matias Fernanda Oliveira, Garcia Patrícia Guedes, Danopoulos Panagiota, Swikidisa Rosita, Pinheiro Vanessa Alves, Nogueira Rodrigo José Lupatini

Issue: Jan/Feb 2016 - Volume 20, Number 1

Page(s): 58-62

Download in electronic PDF format for $75
  • Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 1
  • Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 2
  • Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 3
  • Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 4
  • Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 5

Abstract

The Amazon rainforest is the largest reserve of natural products in the world. Its rich biodiversity of medicinal plants has been utilized by local populations for hundreds of years for the prevention and treatment of various diseases and ailments. Oil extracts from plant species such as Copaifera officinalis and Pentaclethra macroloba are used in compounded formulations for their antiinflammatory, antimicrobial, emollient, moisturizing, and wound-healing activities. The objective of this study was to investigate the in vitro bacteriostatic effect of two Amazonian oils, Copaiba and Pracaxi, against Staphylococcus aureus, a clinically important microorganism responsible for wound infection, to support the use of these oils as novel natural products for compounded wound-treatment modalities. The antibacterial activity of Copaiba and Pracaxi oils against a standard strain of Staphylococcus aureus was assessed using broth microdilution to determine the Minimum Inhibitory Concentration and Minimum Bactericidal Concentration of the oil extracts. Copaiba oil demonstrated antibacterial activity against Staphylococcus aureus, with a Minimum Inhibitory Concentration of 0.3125 mg/mL and a Minimum Bactericidal Concentration of 0.3125 mg/mL. Conversely, Pracaxi oil failed to inhibit Staphylococcus aureus growth. While additional studies are required to further evaluate the antimicrobial activity of Pracaxi oil, even low concentrations of Copaiba oil effectively inhibited Staphylococcus aureus growth, supporting its potential use as a promising adjuvant in compounded topical formulations for wound and scar healing.

Related Keywords

  • copaiba oil
  • Copaifera officinalis
  • pracaxi oil
  • Pentaclethra macroloba
  • natural medicines
  • herbal remedies
  • plant-derived medications
  • medicinal plants
  • bacteriostatic
  • Staphylococcus aureus
  • wound healing
  • bacterial skin infection
  • formulations
  • antimicrobial
  • antibacterial

Related Categories

  • EXCIPIENTS
  • PEER-REVIEWED
  • STABILITIES, COMPATIBILITIES
  • WOUND CARE
  • ALTERNATIVE/COMPLEMENTARY THERAPIES
  • INFECTIOUS DISEASE

Printer-Friendly Version

Related Articles from IJPC

Issue/Page
View/Buy		 Title/Author
(Click for Abstract / Details / Purchase)
Jan/Feb 2016
Pg. 58-62
Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care
Author(s): Guimarães Anna Luísa Aguiar, Cunha Elisa Alves, Matias Fernanda Oliveira, Garcia Patrícia Guedes, Danopoulos Panagiota, Swikidisa Rosita, Pinheiro Vanessa Alves, Nogueira Rodrigo José Lupatini
Jul/Aug 2022
Pg. 277-281
Compounding with Pracaxi Versus Copaiba Oil
Author(s): Magutu Tom
Nov/Dec 2014
Pg. 516-519
Effect of Emulsifier Pairs on Physical Stability of Emulsions Containing Three Different Natural Oils
Author(s): Boonme Prapaporn, Maneenuan Duangkhae
Jan/Feb 2003
Pg. 10-15
View Sample
Compounding for the Effects of Weapons of Mass Destruction
Author(s): Sammarco Domenic A
Jul/Aug 2016
Pg. 333-337
Evaluation of the Antibacterial Activity of Green Propolis Extract and Meadowsweet Extract Against Staphylococcus aureus Bacteria: Importance in Would Care Compounding Preparations
Author(s): Lupatini Nogueira Rodrigo José, Danopoulos Panagiota, Swikidisa Rosita, Alves Pinheiro Vanessa
Jul/Aug 2004
Pg. 269-274
Current Topical Treatments in Wound Healing - Part 1
Author(s): Helmke Christopher D
Mar/Apr 2002
Pg. 92-95
Options in Wound Care
Author(s): Kincaid Michele R
Nov/Dec 2003
Pg. 463
Premixed Oil Phase for Preparing Oil-in-Water (O/W) Emulsions
Author(s): Allen Loyd V Jr
Jul/Aug 2015
Pg. 325
Balsam Peru, Castor Oil, and Trypsin Ointment
Author(s): Allen Loyd V
Nov/Dec 2015
Pg. 509
Estradiol Valerate 40-mg/mL in Oil Injection
Author(s): Allen Loyd V Jr
Jul/Aug 2020
Pg. 282-285
Compounding Pearls -- Wound Care: Burn Healing, Part 2
Author(s): Riepl Mike
Jul/Aug 2023
Pg. 270-276
Case Report in Equine: Highlighting the Benefits of Medisca CopaSil in Burn Scar Management
Author(s): Heuerman Jason, Haiub Halema, Cull Erica, Lupatini Rodrigo, Shrum Brandon, Sidhu Raman
Jul/Aug 2017
Pg. 313
Castor Oil 50% in Modified Pluronic Lecithin Organogel Gel
Author(s): Allen Loyd V Jr
Nov/Dec 2003
Pg. 462
Natural Emollient Oil
Author(s): Allen Loyd V Jr
Jul/Aug 2020
Pg. 278-281
Compounding Pearls -- Wound Care: Diabetic Foot Ulcers, Part 2
Author(s): Riepl Mike
Sep/Oct 1999
Pg. 364
Preventing Leakage in Oil-Filled Capsules
Author(s): Allen Loyd V Jr
Jul/Aug 2003
Pg. 299
Hydroxyprogesterone Caproate 250-mg/mL-in-Oil Injection
Author(s): Allen Loyd V Jr
Jul/Aug 2002
Pg. 303-304
Topical Oil-in-Water Cream Bases, Featured Excipient:
Author(s): Allen Loyd V Jr
Jul/Aug 2000
Pg. 315-317
Experimenting with a New Emulsifying Agent (Tahini) in Mineral Oil Emulsion
Author(s): Al-Achi Antoine, Greenwood Robert, Akin-Isijola Austin
Sep/Oct 2004
Pg. 346
Aromatic Head Lice Oil
Author(s): Paoletti James E