Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC provides on-line access to full-text, full-color, printable PDF copies of your subscribed issues, individual articles, and purchased archives.

Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care

Author(s):  Guimarães Anna Luísa Aguiar, Cunha Elisa Alves, Matias Fernanda Oliveira, Garcia Patrícia Guedes, Danopoulos Panagiota, Swikidisa Rosita, Pinheiro Vanessa Alves, Nogueira Rodrigo José Lupatini

Issue:  Jan/Feb 2016 - Volume 20, Number 1
View All Articles in Issue

Page(s):  58-62

Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 1
Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 2
Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 3
Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 4
Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care Page 5

Download in electronic PDF format for $75

Abstract:  The Amazon rainforest is the largest reserve of natural products in the world. Its rich biodiversity of medicinal plants has been utilized by local populations for hundreds of years for the prevention and treatment of various diseases and ailments. Oil extracts from plant species such as Copaifera officinalis and Pentaclethra macroloba are used in compounded formulations for their antiinflammatory, antimicrobial, emollient, moisturizing, and wound-healing activities. The objective of this study was to investigate the in vitro bacteriostatic effect of two Amazonian oils, Copaiba and Pracaxi, against Staphylococcus aureus, a clinically important microorganism responsible for wound infection, to support the use of these oils as novel natural products for compounded wound-treatment modalities. The antibacterial activity of Copaiba and Pracaxi oils against a standard strain of Staphylococcus aureus was assessed using broth microdilution to determine the Minimum Inhibitory Concentration and Minimum Bactericidal Concentration of the oil extracts. Copaiba oil demonstrated antibacterial activity against Staphylococcus aureus, with a Minimum Inhibitory Concentration of 0.3125 mg/mL and a Minimum Bactericidal Concentration of 0.3125 mg/mL. Conversely, Pracaxi oil failed to inhibit Staphylococcus aureus growth. While additional studies are required to further evaluate the antimicrobial activity of Pracaxi oil, even low concentrations of Copaiba oil effectively inhibited Staphylococcus aureus growth, supporting its potential use as a promising adjuvant in compounded topical formulations for wound and scar healing.

Related Keywords: copaiba oil, Copaifera officinalis, pracaxi oil, Pentaclethra macroloba, natural medicines, herbal remedies, plant-derived medications, medicinal plants, bacteriostatic, Staphylococcus aureus, wound healing, bacterial skin infection, formulations, antimicrobial, antibacterial

Related Categories: EXCIPIENTS, PEER-REVIEWED, STABILITIES, COMPATIBILITIES, WOUND CARE, ALTERNATIVE/COMPLEMENTARY THERAPIES, INFECTIOUS DISEASE

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care
Guimarães Anna Luísa Aguiar
, Cunha Elisa Alves, Matias Fernanda Oliveira, Garcia Patrícia Guedes, Danopoulos Panagiota, Swikidisa Rosita, Pinheiro Vanessa Alves, Nogueira Rodrigo José Lupatini
Jan/Feb 2016
Pg. 58-62

Compounding with Pracaxi Versus Copaiba Oil
Magutu Tom
Jul/Aug 2022
Pg. 277-281

Effect of Emulsifier Pairs on Physical Stability of Emulsions Containing Three Different Natural Oils
Boonme Prapaporn
, Maneenuan Duangkhae
Nov/Dec 2014
Pg. 516-519

Compounding for the Effects of Weapons of Mass Destruction
Sammarco Domenic A
Jan/Feb 2003
Pg. 10-15

View Sample
Evaluation of the Antibacterial Activity of Green Propolis Extract and Meadowsweet Extract Against Staphylococcus aureus Bacteria: Importance in Would Care Compounding Preparations
Lupatini Nogueira Rodrigo José
, Danopoulos Panagiota, Swikidisa Rosita, Alves Pinheiro Vanessa
Jul/Aug 2016
Pg. 333-337

Current Topical Treatments in Wound Healing - Part 1
Helmke Christopher D
Jul/Aug 2004
Pg. 269-274

Options in Wound Care
Kincaid Michele R
Mar/Apr 2002
Pg. 92-95

Premixed Oil Phase for Preparing Oil-in-Water (O/W) Emulsions
Allen Loyd V Jr
Nov/Dec 2003
Pg. 463

Balsam Peru, Castor Oil, and Trypsin Ointment
Allen Loyd V
Jul/Aug 2015
Pg. 325

Estradiol Valerate 40-mg/mL in Oil Injection
Allen Loyd V Jr
Nov/Dec 2015
Pg. 509

Compounding Pearls -- Wound Care: Burn Healing, Part 2
Riepl Mike
Jul/Aug 2020
Pg. 282-285

Case Report in Equine: Highlighting the Benefits of Medisca CopaSil in Burn Scar Management
Heuerman Jason
, Haiub Halema, Cull Erica, Lupatini Rodrigo, Shrum Brandon, Sidhu Raman
Jul/Aug 2023
Pg. 270-276

Castor Oil 50% in Modified Pluronic Lecithin Organogel Gel
Allen Loyd V Jr
Jul/Aug 2017
Pg. 313

Natural Emollient Oil
Allen Loyd V Jr
Nov/Dec 2003
Pg. 462

Compounding Pearls -- Wound Care: Diabetic Foot Ulcers, Part 2
Riepl Mike
Jul/Aug 2020
Pg. 278-281

Preventing Leakage in Oil-Filled Capsules
Allen Loyd V Jr
Sep/Oct 1999
Pg. 364

Hydroxyprogesterone Caproate 250-mg/mL-in-Oil Injection
Allen Loyd V Jr
Jul/Aug 2003
Pg. 299

Topical Oil-in-Water Cream Bases, Featured Excipient:
Allen Loyd V Jr
Jul/Aug 2002
Pg. 303-304

Experimenting with a New Emulsifying Agent (Tahini) in Mineral Oil Emulsion
Al-Achi Antoine
, Greenwood Robert, Akin-Isijola Austin
Jul/Aug 2000
Pg. 315-317

Aromatic Head Lice Oil
Paoletti James E
Sep/Oct 2004
Pg. 346

Return to Top