Abstract

Topical Cidofovir for Treatment of Resistant Viral Infections

Author(s): McElhiney Linda F

Issue: Sep/Oct 2006 - Dermatology

Page(s): 324-328

Download in electronic PDF format for $75

Abstract

Cidofovir is a broad-spectrum antiviral agent with activity against several DNA viruses. An application to approve the use of topical cidofovir for acyclovir-resistant herpes virus infection was denied by the US Food and Drug Administration owing to the lack of phase III clinical trial data. The manufacturer stated that, as of 1997, no further controlled studies were planned or in progress to evaluate topical cidofovir in herpes simplex infections. It is unknown whether there are plans to conduct controlled studies of topical cidofovir for HPV or MVC infections. However, numerous case reports and published studies describe successful use of topical cidofovir to treat resistant and severe forms of viral infections such as molluscum contagiosum, condylomata acuminata, verruca vulgaris, herpes simplex virus infection, genital warts, and gingival infection with human papillomavirus. Because of the mutagenic properties of cidofovir, compounding the preparation is considered hazardous. Since most retail pharmacies

Related Keywords

Related Categories

Printer-Friendly Version

Related Articles from IJPC

Issue/Page View/Buy	Title/Author (Click for Abstract / Details / Purchase)
Sep/Oct 2006 Pg. 324-328	Topical Cidofovir for Treatment of Resistant Viral Infections Author(s): McElhiney Linda F
Jul/Aug 2003 Pg. 266-270	Sensitization Therapy for Warts Author(s): Kuntz Rachael
Mar/Apr 2004 Pg. 126-129	Basics of Compounding for the Treatment of Warts Author(s): Allen Loyd V Jr
May/Jun 2023 Pg. 182-190	Warts: Pathophysiology, Types, Treatments, and Pharmaceutical Compounds Author(s): Touprong Robin, Thompson Tara, Williams LaVonn A
Jul/Aug 2004 Pg. 269-274	Current Topical Treatments in Wound Healing - Part 1 Author(s): Helmke Christopher D
Nov/Dec 2009 Pg. 554	Cidofovir 0.2-mg/mL Intravitreous Injection Author(s): Allen Loyd V Jr
Nov/Dec 2006 Pg. 461	Valacyclovir 50-mg/mL Oral Liquid Author(s): Allen Loyd V Jr
Nov/Dec 2011 Pg. 450-457	Compounding for Treatment of Equine Infectious Diseases: An Overview Author(s): Bramwell Bethany L
May/Jun 2018 Pg. 196-202	Case Report of a Human Papillomavirus Infection Treated with Green Tea Extract and Curcumin Vaginal Compounded Medications Author(s): Agbi Kelechi E, Hover Sara, Carvalho Maria
Jan/Feb 2017 Pg. 22-27	Case Report: Diabetic Foot Ulcer Infection Treated with Topical Compounded Medications Author(s): Agbi Kelechi E, Carvalho Maria, Phan Ha, Tuma Cristiane
Jul/Aug 2001 Pg. 310-312	Wetting and/or Solubilizing Agents, Featured Excipient: Author(s): Allen Loyd V Jr
Nov/Dec 2006 Pg. 434-435	Ronidazole in the Treatment of Trichomonad Infections in Cats Author(s): Davidson Gigi S
Nov/Dec 2007 Pg. 509	Foscarnet 2.5% Topical Cream Author(s): Allen Loyd V Jr
Mar/Apr 2009 Pg. 120-124	Treating Methicillin-Resistant Staphylococcus Aureus Infections with Compounded Vancomycin Preparations Author(s): McElhiney Linda F
Jul/Aug 2012 Pg. 336	Foscarnet Sodium 24-mg/mL Injection Author(s): Allen Loyd V Jr
Jan/Feb 2014 Pg. 60	Aztreonam Injection Author(s): Allen Loyd V Jr
Sep/Oct 2015 Pg. 357-365	Novel Approaches to Topical Psoriasis Therapy Author(s): Koyama Gregory, Liu Jenny, Scaffidi Alyse, Khazraee Maryam, Epstein Benjamin
Mar/Apr 2023 Pg. 98-107	Compounding for the Treatment of COVID-19 and Long COVID, Part 2: Manifestations of Infection, Nomenclature, Transmission, and Treatment Author(s): Riepl Mike
Jan/Feb 2003 Pg. 10-15 View Sample	Compounding for the Effects of Weapons of Mass Destruction Author(s): Sammarco Domenic A
Sep/Oct 2003 Pg. 354-356	Sterile Vancomycin Pluronic Gel for Implantation in the Chest-Wall Cavity to Treat Resistant Pneumococcus Author(s): Gray Cary, Shome Sibaji, Muller George