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Basics of Compounding: Basics of Compounding with Complex Organic Molecules

Author(s):  Allen Loyd V Jr

Issue:  May/Jun 2011 - Volume 15, Number 3
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Abstract:  Pharmacists involved in compounding must consider a number of factors when determining the actual quantity of an active ingredient to use for a compounded prescription. Many drug substances do not consist of 100% drug or chemical, and adjustments must be made to obtain the required amount of active drug (active pharmaceutical ingredient). This is true with many complex organic molecules, which also have unique physicochemical requirements.

Related Keywords: Loyd V. Allen Jr., PhD, RPh, complex organic molecules, stabilizers, excipients, proteins, peptide-like molecules, stabilizing agents, buffers, chelating agents, antioxidants, preservatives, sorption, drug stability, packaging, storage

Related Categories: EXCIPIENTS, STABILITIES, COMPATIBILITIES, SUPPORT, QUALITY CONTROL, STORAGE

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