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Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 8: Humectants

Author(s):  Allen Loyd V Jr

Issue:  Mar/Apr 2021 - Volume 25, Number 2
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Abstract:  Humectants, hygroscopic substances used to minimize water loss and to prevent the drying out of different types of products, are in common use not only in pharmaceuticals but also in foods, cosmetics, etc. The proper selection of a humectant in a pharmaceutical formula depends upon the dosage form, ingredients, physical and chemical characteristics, as well as stability issues. This article discusses the importance of humectants and their applications in pharmaceutics.

Related Keywords: Loyd V. Allen Jr., PhD, RPh, humectants, water loss, drying out, hygroscopic materials, active ingredient solubility, topical preparations, skin permeability, transdermal penetration, viscosity, product consistency, cosmetics, skin hydration, tobacco products, foods, food additives, suspensions, ointments, creams, oral films, moisture retention, water affinity

Related Categories: DERMATOLOGY, EXCIPIENTS, DOSAGE FORMS/DRUG CARRIERS

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