Abstract

Considerations for Percutaneous Absorption

Author(s): Newton Stephen J, Cook Jennifer M

Issue: Jul/Aug 2010 - Sterile Compounding

Page(s): 301-304

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Abstract

Percutaneous absorption is affected by numerous factors. Whether they are internal or external factors, the compounding pharmacist must collectively consider these variables in order to provide a safe and effective topical preparation for the patient. By considering the physiochemical and dermal factors that affect percutaneous absorption of a medication, an effective topical medication can be formulated to treat the patient’s specific indication. Furthermore, this article will review the background information necessary to formulate transdermal prescriptions for their patients.

Related Keywords

  • percutaneous absorption
  • topical preparations
  • transdermal administration
  • skin hydration
  • skin damage
  • dermal lipids
  • pluronic solubility
  • formulation
  • solid lipid nanoparticles
  • particle size
  • partition coefficient

Related Categories

  • DERMATOLOGY
  • EXCIPIENTS
  • FORMULATIONS
  • DOSAGE FORMS/DRUG CARRIERS

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