Stability of Zidovudine and Ranitidine in 0.9% sodium Chloride and 5% Dextrose Injections Stored at Ambient Temperature (23 ± 2°C) and 4°C in 50-mL Polyvinylchloride Bags Up to 24 Hours.

Musami, Patrick; Stewart, James T; Taylor, E Will

A subscription to IJPC provides on-line access to full-text, full-color, printable PDF copies of all issues and individual articles published by the Journal since 1997.

LEARN MORE

Stability of Zidovudine and Ranitidine in 0.9% sodium Chloride and 5% Dextrose Injections Stored at Ambient Temperature (23 ± 2°C) and 4°C in 50-mL Polyvinylchloride Bags Up to 24 Hours.

Author(s): Musami Patrick, Stewart James T, Taylor E Will

Issue: May/Jun 2004 - Andropause
View All Articles in Issue

Page(s): 236-239

Stability of Zidovudine and Ranitidine in 0.9% sodium Chloride and 5% Dextrose Injections Stored at Ambient Temperature (23 ± 2°C) and 4°C in 50-mL Polyvinylchloride Bags Up to 24 Hours. Page 1

Download in electronic PDF format for $75

Abstract: The stability of a 2-mg/mL zidovudine and 0.5-mg/mL ranitidine admixture stored in 0.9% sodium chloride and 5% dextrose injections in 50-mL polyvinylchloride bags at ambient temperature and 4°C up to 24 hours was studied. The samples were analyzed at 0, 4, 8 and 24 hours after preparation of the controls and admixtures by means of a reverse-phase, stability-indicating, high-performance liquid chromatographic method. The drug mixtures were stable for up to 24 hours, showing levels of greater than 90% of the initial drug concentrations at the time of preparation. The pH of the admixtures was in the pH 5–6 range. These data support the stability of the zidovudine and ranitidine admixture under the storage conditions studied.

Related Keywords: Ranitidine and zidovudine admixture, stability of, Zidovudine and ranitidine admixture, stability of

Related Categories: INFUSION, PEER-REVIEWED, STABILITIES, COMPATIBILITIES, STERILE PREPARATIONS

Printer-Friendly Version

Title/Author (Click for Abstract / Details / Purchase)	Issue/Page View/Buy
Related Articles from IJPC
Stability of Zidovudine and Ranitidine in 0.9% sodium Chloride and 5% Dextrose Injections Stored at Ambient Temperature (23 ± 2°C) and 4°C in 50-mL Polyvinylchloride Bags Up to 24 Hours. Musami Patrick, Stewart James T, Taylor E Will	May/Jun 2004 Pg. 236-239
Stability of Aminocaproic Acid Injection Admixtures in 5% Dextrose Injection and 0.9% Sodium Chloride Injection Zhang Yan-ping, Trissel Lawrence A	Mar/Apr 1997 Pg. 132-134
Stability of Tubocurarine Chloride Injection at Ambient Temperature and 4°C in Polypropylene Syringes Stewart James T, Storms Meredith L, Warren Flynn W	Jul/Aug 2002 Pg. 308-310
Stability of Glycopyrrolate Injection at Ambient Temperature and 4°C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Jan/Feb 2003 Pg. 65-67
Stability of Lidocaine Hydrochloride Injection at Ambient Temperature and 4°C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Sep/Oct 2002 Pg. 388-390
Stability of Zidovudine and Dobutamine HCl Injections in 0.9% Sodium Chloride and 5% Dextrose Injections Stored at Ambient Temperature (23 ± 2°C) and 4°C in 50-mL Polyvinyl Chloride Bags Up to 24 Hours Musami Patrick, Stewart James T, Taylor E Will	Jan/Feb 2004 Pg. 73-76
Stability of Dexmedetomidine in Polyvinyl Chloride Bags Containing 0.9% Sodium Chloride Intended for Subcutaneous Infusions Wolfe Amanda, Zhang Jeremy, Lapenskie Julie, Downar James, Kanji Salmaan	Jul/Aug 2021 Pg. 330-335
Stability of Dexmedetomidine in 0.9% Sodium Chloride in Two Types of Intravenous Infusion Bags Marquis Kathleen, Hohlfelder Benjamin, Szumita Paul M	Sep/Oct 2017 Pg. 436-439
Stability of Cefepime Hydrochloride Dextrose in 5% Dextrose Injection and 0.9% Sodium Chloride Injection Gupta Vishnu D, Maswoswe J, Bailey RE	Nov/Dec 1997 Pg. 435-436
Stability of Neostigmine Methylsulfate Injection at Ambient Temperature and 4°C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Nov/Dec 2002 Pg. 475-477
Stability of Alatrofloxacin Mesylate in 5% Dextrose Injection and 0.45% Sodium-Chloride Injection Gupta Vishnu D, Bailey RE	Jan/Feb 2000 Pg. 66-68
Stability of Alprostadil in 0.9% Sodium Chloride Stored in Polyvinyl Chloride Containers McCluskey Susan V, Kirkham Kylian, Munson Jessica M	Mar/Apr 2017 Pg. 150-153
Long-term Stability of Esomeprazole in 5% Dextrose Infusion Polyolefin Bags at 5°C ± 3°C after Microwave Freeze-thaw Treatment Hecq Jean-Daniel, Rolin Catherine, Godet Marie, Gillet Patricia, Jamart Jacques, Galanti Laurence M	Nov/Dec 2015 Pg. 521-524
Compatibility and Stability of Potassium Chloride and Magnesium Sulfate in 0.9% Sodium Chloride Injection and 5% Dextrose Injection Solutions Quay Irene, Tan Edward	Jul/Aug 2001 Pg. 323-324
Stability of Milrinone Lactate 200 mcg/mL in 5% Dextrose Injection and 0.9% Sodium Chloride Injection Wong Frances, Gill Mark A	Mar/Apr 1998 Pg. 168-169
Stability of Cefmetazole Sodium in 5% dextrose Injection and 0.9% Sodium Chloride Injection Gupta Vishnu D, Maswoswe J, Bailey RE	May/Jun 1997 Pg. 208-209
Stability of Ephedrine Sulfate at Ambient Temperature and 4°C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Sep/Oct 2001 Pg. 394-396
Long-term Stability of Morphine Hydrochloride in 0.9% NaCl Infusion Polyolefin Bags After Freeze-thaw Treatment and in Polypropylene Syringes at 5°C ± 3°C Hecq J-D, Godet M, Gillet P, Jamart J, Galanti L	Jan/Feb 2014 Pg. 78-82
Stability of Ketorolac Tromethamine in 5% Dextrose Injection and 0.9% Sodium Chloride Injections Gupta Vishnu D, Maswoswe J, Bailey RE	May/Jun 1997 Pg. 206-207
Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Jan/Feb 2003 Pg. 68-70
Return to Top