Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes

Storms, Meredith L; Stewart, James T; Warren, Flynn W

A subscription to IJPC provides on-line access to full-text, full-color, printable PDF copies of your subscribed issues, individual articles, and purchased archives.

LEARN MORE

Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes

Author(s): Storms Meredith L, Stewart James T, Warren Flynn W

Issue: Jan/Feb 2003 - Terrorism
View All Articles in Issue

Page(s): 68-70

Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes Page 1

Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes Page 2

Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes Page 3

Download in electronic PDF format for $75

Abstract: The stability of 20-mg/mL succinylcholine chloride injection in 12-mL polypropylene syringes stored at ambient temperature and 4°C for up to 90 days was investigated. Concentration levels of succinylcholine chloride injection were determined at 0, 1, 4, 7, 15, 30, 45, 60, and 90 days after preparation of the syringes by means of a high-performance liquid chromatographic stability-indicating assay. Methylparaben, which was added as a preservative, did not interfere with the assay. The loss in potency was less than 10% after 45 days of storage at 25°C and less than 1% after 90 days of storage at 4°C. The pH of succinylcholine chloride injection did not change appreciably during the 90-day study period.

Related Keywords: Succinylcholine chloride injection, stability of

Related Categories: PEER-REVIEWED, STABILITIES, COMPATIBILITIES

Printer-Friendly Version

Title/Author (Click for Abstract / Details / Purchase)	Issue/Page View/Buy
Related Articles from IJPC
Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Jan/Feb 2003 Pg. 68-70
Stability of Tubocurarine Chloride Injection at Ambient Temperature and 4°C in Polypropylene Syringes Stewart James T, Storms Meredith L, Warren Flynn W	Jul/Aug 2002 Pg. 308-310
Stability of Neostigmine Methylsulfate Injection at Ambient Temperature and 4°C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Nov/Dec 2002 Pg. 475-477
Stability of Lidocaine Hydrochloride Injection at Ambient Temperature and 4°C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Sep/Oct 2002 Pg. 388-390
Stability of Glycopyrrolate Injection at Ambient Temperature and 4°C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Jan/Feb 2003 Pg. 65-67
Succinylcholine Chloride 50-mg/mL Injection Allen Loyd V Jr	Jul/Aug 2013 Pg. 335
Compatibility and Stability of Potassium Chloride and Magnesium Sulfate in 0.9% Sodium Chloride Injection and 5% Dextrose Injection Solutions Quay Irene, Tan Edward	Jul/Aug 2001 Pg. 323-324
Stability of Aminocaproic Acid Injection Admixtures in 5% Dextrose Injection and 0.9% Sodium Chloride Injection Zhang Yan-ping, Trissel Lawrence A	Mar/Apr 1997 Pg. 132-134
Room Temperature Stability of Injectable Succinylcholine Dichloride Roy Julie J, Boismenu Daniel, Mamer Orval A, Nguyen Bao T, Forest Jean-Marc, Hildgen Patrice	Jan/Feb 2008 Pg. 83-85
Stability of Alatrofloxacin Mesylate in 5% Dextrose Injection and 0.45% Sodium-Chloride Injection Gupta Vishnu D, Bailey RE	Jan/Feb 2000 Pg. 66-68
Stability of Dalteparin 1,000 Unit/mL in 0.9% Sodium Chloride for Injection in Polypropylene Syringes Kirkham Kylian, Munson Jessica M, McCluskey Susan V, Graner Kevin K	Sep/Oct 2017 Pg. 426-429
Stability of Ephedrine Sulfate at Ambient Temperature and 4°C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W	Sep/Oct 2001 Pg. 394-396
Stability of Levothyroxine Sodium Injection in Polypropylene Syringes Gupta Vishnu D	Nov/Dec 2000 Pg. 482-483
Stability of Dexmedetomidine in Polyvinyl Chloride Bags Containing 0.9% Sodium Chloride Intended for Subcutaneous Infusions Wolfe Amanda, Zhang Jeremy, Lapenskie Julie, Downar James, Kanji Salmaan	Jul/Aug 2021 Pg. 330-335
Chemical Stability of Epinephrine 10 mcg/mL Diluted in 0.9% Sodium Chloride and Stored in Polypropylene Syringes at 4 degrees C and 25 degrees C Hook Roxanne, Neault Ashleigh, Scharrer Devan, Law Shirley, Walker Scott E, Ma Nathan H, Riss Vera	Jul/Aug 2023 Pg. 347-351
Stability of Alprostadil in 0.9% Sodium Chloride Stored in Polyvinyl Chloride Containers McCluskey Susan V, Kirkham Kylian, Munson Jessica M	Mar/Apr 2017 Pg. 150-153
Stability of Furosemide 5 mg/mL in Polypropylene Syringes van der Schaar JAJ, Grouls R, Franssen EJF, Crul M	Sep/Oct 2019 Pg. 414-417
Physical and Chemical Stability of Trepostinil Sodium Injection Packaged in Plastic Syringe Pump Reservoirs. Xu Quanyun A, Trissel Lawrence A, Pham Lien	May/Jun 2004 Pg. 228-230
Chemical Stability of Metoclopramide Hydrochloride Injection Diluted with 0.9% Sodium Chloride Injection in Polypropylene Syringes at Room Temperature Gupta Vishnu D	Jan/Feb 2005 Pg. 72-74
Stability of Zidovudine and Ranitidine in 0.9% sodium Chloride and 5% Dextrose Injections Stored at Ambient Temperature (23 ± 2°C) and 4°C in 50-mL Polyvinylchloride Bags Up to 24 Hours. Musami Patrick, Stewart James T, Taylor E Will	May/Jun 2004 Pg. 236-239
Return to Top