Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes

Author(s):  Storms Meredith L, Stewart James T, Warren Flynn W

Issue:  Jan/Feb 2003 - Terrorism
View All Articles in Issue

Page(s):  68-70

Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes Page 1
Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes Page 2
Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes Page 3

Download in electronic PDF format for $65

Abstract:  The stability of 20-mg/mL succinylcholine chloride injection in 12-mL polypropylene syringes stored at ambient temperature and 4°C for up to 90 days was investigated. Concentration levels of succinylcholine chloride injection were determined at 0, 1, 4, 7, 15, 30, 45, 60, and 90 days after preparation of the syringes by means of a high-performance liquid chromatographic stability-indicating assay. Methylparaben, which was added as a preservative, did not interfere with the assay. The loss in potency was less than 10% after 45 days of storage at 25°C and less than 1% after 90 days of storage at 4°C. The pH of succinylcholine chloride injection did not change appreciably during the 90-day study period.

Related Keywords: Succinylcholine chloride injection, stability of

Related Categories: PEER-REVIEWED, STABILITIES, COMPATIBILITIES

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
Stability of Succinylcholine Chloride Injection at Ambient Temperature and 4 Degree C in Polypropylene Syringes
Storms Meredith L
, Stewart James T, Warren Flynn W
Jan/Feb 2003
Pg. 68-70

Succinylcholine Chloride 50-mg/mL Injection
Allen Loyd V Jr
Jul/Aug 2013
Pg. 335

Compatibility and Stability of Potassium Chloride and Magnesium Sulfate in 0.9% Sodium Chloride Injection and 5% Dextrose Injection Solutions
Quay Irene
, Tan Edward
Jul/Aug 2001
Pg. 323-324

Stability of Aminocaproic Acid Injection Admixtures in 5% Dextrose Injection and 0.9% Sodium Chloride Injection
Zhang Yan-ping
, Trissel Lawrence A
Mar/Apr 1997
Pg. 132-134

Stability of Alatrofloxacin Mesylate in 5% Dextrose Injection and 0.45% Sodium-Chloride Injection
Gupta Vishnu D
, Bailey RE
Jan/Feb 2000
Pg. 66-68

Stability of Tubocurarine Chloride Injection at Ambient Temperature and 4°C in Polypropylene Syringes
Stewart James T
, Storms Meredith L, Warren Flynn W
Jul/Aug 2002
Pg. 308-310

Room Temperature Stability of Injectable Succinylcholine Dichloride
Roy Julie J
, Boismenu Daniel, Mamer Orval A, Nguyen Bao T, Forest Jean-Marc, Hildgen Patrice
Jan/Feb 2008
Pg. 83-85

Stability of Dexmedetomidine in Polyvinyl Chloride Bags Containing 0.9% Sodium Chloride Intended for Subcutaneous Infusions
Wolfe Amanda
, Zhang Jeremy, Lapenskie Julie, Downar James, Kanji Salmaan
Jul/Aug 2021
Pg. 330-335

Stability of Alprostadil in 0.9% Sodium Chloride Stored in Polyvinyl Chloride Containers
McCluskey Susan V
, Kirkham Kylian, Munson Jessica M
Mar/Apr 2017
Pg. 150-153

Stability of Milrinone Lactate 200 mcg/mL in 5% Dextrose Injection and 0.9% Sodium Chloride Injection
Wong Frances
, Gill Mark A
Mar/Apr 1998
Pg. 168-169